This is the principle of the complement fixation test.
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Alternatively diagnosis can be made by complement fixation tests,
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Complement fixation causes the generation of additional inflammatory mediators
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Methods used in laboratory diagnosis include serological methods ( e . g . complement fixation test ).
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Although hexameric IgM without J chain has higher efficiency of complement fixation than pentameric IgM with J chain.
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The presence or absence of complement fixation upon a challenge can indicate whether particular antigens or antibodies are present in the blood.
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Bacterial culture, immunofluorescent antibody testing ( IFAT ), complement fixation test and haemagglutination can all be used to confirm the diagnosis.
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Antiechinococcus antibodies can be detected with serodiagnostic tests indirect fluorescent antibody, complement fixation, ELISA, Western blot, and other methods.
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Natural serum antibodies play an important early role in the immune response to many bacteria and viruses but require complement fixation for effective antigen clearance.
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Both complement fixation, neutralisation and enzyme linked immunosorbent assays ELISA, can also be used to aid in the process of distinguishing between viral serotypes.
an immune response in which an antigen-antibody combination inactivates a complement (so it is unavailable to participate in a second antigen-antibody combination)
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